Treatment Algorithms for Chronic Osteomyelitis

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Case report: treatment of chronic osteomyelitis.

Presented is a case of chronic methicillin-resistant Staphylococcus aureus osteomyelitis, which was unsuccessfully treated with multiple courses of debridement and potent antibiotic therapies. Amputation of the patient's lower limb was believed to be the only option remaining. A compassionate access program, with approval from the US Food and Drug Administration and the institutional review boa...

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Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a non-bacterial inflammatory disorder of unknown cause occurring in children and adolescents. It is characterized by the insidious onset of pain and swelling to multifocal involved bones, recurring over months to years. Non-steroid anti-inflammatory drugs (NSAIDs) and steroids are the first choice for the initial and relapse treatment. Howeve...

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The Classic: Sulfonamides in the Treatment of Chronic Osteomyelitis

This Classic article is a reprint of the original work by John Albert Key, Sulfonamides in the Treatment of Chronic Osteomyelitis. An accompanying biographical sketch on John Albert Key, MD, is available at DOI 10.1007/s11999-009-0798-6. The Classic Article is 1944 by The Journal of Bone and Joint Surgery, Inc. and is reprinted with permission from Key JA. Sulfonamides in the Treatment of Chron...

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Daptomycin treatment of Staphylococcus aureus experimental chronic osteomyelitis.

BACKGROUND Infection due to methicillin-resistant Staphylococcus aureus (MRSA) is increasingly common in nosocomial and community settings. Daptomycin is a cyclic lipopeptide anti-infective with activity against MRSA, approved for treatment of complicated skin and skin structure infections. Daptomycin may be useful in systemic or local treatment of chronic osteomyelitis. METHODS We measured m...

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ژورنال

عنوان ژورنال: Deutsches Aerzteblatt Online

سال: 2012

ISSN: 1866-0452

DOI: 10.3238/arztebl.2012.0257